INFANT (INdividualized therapy For Asthma iN Toddlers) and AVICA (Acetaminophen Vs. Ibuprofen in Children with Asthma) studies were two separate but linked studies for preschool aged children with persistent asthma. INFANT was designed to determine whether one asthma controller-medication worked better than another for these children and to see if there were characteristics about a child that helped doctors predict which treatment would work better. AVICA was designed to find out if different fever/pain medicines have an effect on asthma symptoms. INFANT and AVICA were sponsored by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH). The INFANT and AVICA studies have been completed.